Matt Flynn will start for Rodgers, with James Starks in for Lacy on Saturday night. The Packers also scratched receiver Jordy Nelson, giving Jarrett Boykin the start in his place.
Safety Morgan Burnett, recovering from an oblique injury, was among seven Packers who did not travel to Tennessee and the only starter in that group.
The Titans scratched only four players who all have been dealing with injuries. That includes defensive linemen Mike Martin (hamstring), Antonio Johnson (knee) and Marcus Dixon. Linebacker David Gilbert (shoulder) also is out.